935658-32-5Relevant articles and documents
The first asymmetric total syntheses and determination of absolute configurations of xestodecalactones B and C
Liang, Qiren,Zhang, Jiyong,Quan, Weiguo,Sun, Yongquan,She, Xuegong,Pan, Xinfu
, p. 2694 - 2697 (2007/10/03)
The first efficient asymmetric total syntheses of xestodecalactones B and C have been accomplished in 10 steps with an overall yield of 22 and 20.2%, respectively. The key steps involve the utility of Evans oxazolidinone-mediated syn-aldol condensations to establish the C-9 configuration and the macrolide ring formation by intramolecular acylation. The absolute configurations of xestodecalactones B and C have been determined via these syntheses.