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Upstream product

• 19810-31-2 Benzyloxyacetyl chloride 
• 149818-33-7 (+)-(3R,4S)-cis-3-benzyloxy-4-[(S)-1',2'-dihydroxyethyl]-1-(p-methoxyphenyl)-2-azetidinone 
• 115857-84-6 (3R,4S)-3-(Benzyloxy)-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>-1-(4-methoxyphenyl)azetidin-2-one 
• 160237-98-9 (3R,4S)-1-(4-methoxyphenyl)-3-(benzyloxy)-4-vinyl-2-azetidinone 

Relevant academic research and scientific papers

Stereoselective synthesis of highly functionalized 5- A nd 6-membered aminocyclitols starting with a readily available 2-azetidinone

Stereoselective transformations of 4-vinyl-2-azetidinone derivative 4 into a variety of highly functionalized 6- A nd 5-membered carbocyclic compounds 7 and 9 were carried out using sequences involving sequential C1-N bond cleavage and Ru-catalyzed ring-closing metathesis. The derived carbocycles were further transformed into polyhydroxylated 6- A nd 5-membered aminocyclitols.

Synthesis and Biological Evaluation of C-3'-Modified Analogs of 9(R)-Dihydrotaxol

Taxol (1) is considered a most exciting new drug in cancer chemotherapy.The promising antitumor activity of 9(R)-dihydrotaxol (3) encouraged us to further explore the structure-activity relationship of this new member of the taxane family.Studies indicate