935692-76-5Relevant academic research and scientific papers
Design, synthesis and evaluation of MCH receptor 1 antagonists - Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition
Roth, Gerald J.,Heckel, Armin,Kley, J?rg T.,Lehmann, Thorsten,Müller, Stephan G.,Oost, Thorsten,Rudolf, Klaus,Arndt, Kirsten,Budzinski, Ralph,Lenter, Martin,Lotz, Ralf R.H.,Schindler, Marcus,Thomas, Leo,Stenkamp, Dirk
, p. 3270 - 3274 (2015/07/08)
Abstract Despite recent success there remains a high therapeutic need for the development of drugs targeting diseases associated with the metabolic syndrome. As part of our search for safe and effective MCH-R1 antagonists for the treatment of obesity, a s
(HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS
-
Page/Page column 74, (2010/11/27)
The present invention relates to (hetero)aryl compounds of general formula (I) wherein the groups and radicals A, B, Q, W, X, Y, Z, R1, R2, R4a, R4b, R5a, R5b, have the meanings given in cl
