935838-06-5Relevant academic research and scientific papers
Alkylpalladium n-heterocyclic carbene complexes: Synthesis, reactivity, and catalytic properties
Esposito, Oriana,Gois, Pedro M. P.,De K. Lewis, Alexandra K.,Caddick, Stephen,N. Cloke, F. Geoffrey,Hitchcock, Peter B.
, p. 6411 - 6418 (2009/05/30)
The dimers [trans-[(neopentyl)Pd(μ-Cl)(rBu)]2, 2, and (cis-[(neopentyl)Pd(μ-Cl)(IPr)]2,3 (ItBu = 1,3-bis-tert-butylimidazol-2-ylidene, IPr = l,3-bis-2,6-diidopropylimidazol-2- ylidene), have been synthesized from [Pd(neopentyl)(Cl)(l,5-COD)], and their reactivity toward a variety of nucleophiles has been evaluated. In particular, this study revealed that 2 can be readily cleaved by primary and secondary amines, affording stable transamination products, which are surprisingly resistant to deprotonation. Dimer 3 was subsequently used as a catalyst in a series of Buchwald-Hartwig animation reactions of aryl chlorides.
Synthesis and reactivity of alkylpalladium N-heterocyclic carbene complexes
Esposito, Oriana,Lewis, Alexandra K. De K.,Hitchcock, Peter B.,Caddick, Stephen,Cloke, F. Geoffrey N.
, p. 1157 - 1159 (2008/02/02)
The transamination of alkylpalladium halide N-heterocyclic carbene complexes has enabled the isolation of products that reveal interesting insights into the factors which might be barriers to the development of a palladium-catalysed alkyl-amination reaction. The Royal Society of Chemistry.
