93584-03-3 Usage
General Description
1-(2-hydrazinyl-4-methylpyrimidin-5-yl)ethanone, also known as HMPE, is a chemical compound with a pyrimidine structure and a hydrazine functional group. It has a molecular formula of C8H12N4O and a molecular weight of 176.21 g/mol. HMPE is used in the synthesis of organic compounds and pharmaceuticals due to its reactivity and ability to form diverse chemical bonds. It has potential applications in the development of bioactive molecules and drug discovery. Additionally, HMPE may also have potential uses in various research fields, including chemistry and biochemistry. Overall, HMPE is a valuable chemical building block with potential applications in the pharmaceutical and scientific industries.
Check Digit Verification of cas no
The CAS Registry Mumber 93584-03-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,5,8 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 93584-03:
(7*9)+(6*3)+(5*5)+(4*8)+(3*4)+(2*0)+(1*3)=153
153 % 10 = 3
So 93584-03-3 is a valid CAS Registry Number.
93584-03-3Relevant articles and documents
Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine- 5-carboxylate: An inhibitor of AP-1 and NF-κB mediated gene expression
Palanki, Moorthy S.S.,Gayo-Fung, Leah M.,Shevlin, Graziella I.,Erdman, Paul,Sato, Mark,Goldman, Mark,Ransone, Lynn J.,Spooner, Cheryl
, p. 2573 - 2577 (2007/10/03)
Several analogues of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine- 5-carboxylate (1) were synthesized and tested as inhibitors of AP-1 and NF-κB mediated transcriptional activation in Jurkat T cells. From our SAR work, ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))-N-methylamino]-4-(trifluoromethyl)- pyrimidine-5-carboxylate was identified as a novel and potent inhibitor.
