935855-76-8

Upstream product

• 935855-31-5 [4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-phenyl-acetic acid methyl ester 
• 4870-65-9 2-bromophenylacetic acid 
• 154590-33-7 1-(2-fluoro-4-nitrophenyl)piperazine 

Downstream Products

• 935855-77-9 N-ethyl-2-[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-2-phenyl-acetamide 
• 1163126-72-4 2-(2-(4-(2-fluoro-4-nitrophenyl)piperazin-1-yl)-2-phenylacetylamino)-3-hydroxypropionic acid methyl ester 

Relevant academic research and scientific papers

PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

The present invention is directed to piperidinyl and piperazinyl derivatives of formula (II) useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of said compounds for the treatment and / or prevention of disorders, diseases and conditions mediated by the NPY Y2 receptor.

SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurological disorders; bone loss; substance related disorders; sleep/wake disorders; cardiovascular disease; obesity; or an obesity-related disorder. Compounds of the invention are also useful in modulating endocrine functions, particularly endocrine functions controlled by the pituitary and hypothalamic glands, and are therefore useful in the treatment or prevention of inovulation and infertility.