93592-80-4

Upstream product

• 14891-10-2 ethyl-3-oxo-1-pyrrolidinecarboxylate 
• 93591-93-6 ethyl 3-(4-chloroanilino)pyrrolidine-1-carboxylate 
• 93591-92-5 1-ethoxycarbonyl-3-mesyloxypyrrolidine 
• 873-32-5 2-Chlorobenzonitrile 
• 93591-94-7 4-chloro-(1-methyl-3-pyrrolidinyl)aniline 

Downstream Products

• 93592-49-5 7-Chloro-5-(2-chloro-phenyl)-1-(1-methyl-pyrrolidin-3-yl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 93592-70-2 N-[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-(1-methyl-pyrrolidin-3-yl)-acetamide 

Relevant academic research and scientific papers

Aminohaloborane in Organic Synthesis. IX. Exclusive ortho Acylation Reaction of N-Monoaminoalkylanilines

The exclusive ortho acylation reaction of aniline derivatives using boron trichloride made possible the one-step synthesis of 2-acyl-N-monoaminoalkylanilines (1) and the corresponding imines (2) from N-monoaminoalkylanilines, even in the case of compounds with a bulky substituent at the nitrogen atom.Conventional methods only give 1 via elaborate procedures.Keywords: regioselective reaction; 2-acylaniline derivative; 2-acylaniline-imine derivative; boron trichloride