935999-02-3

Basic information

• Product Name: 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-methyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide
• Synonyms: 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-methyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide
• CAS NO: 935999-02-3
• Molecular Weight: 378.858
• Mol File: 935999-02-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-methyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-methyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide(935999-02-3)
• EPA Substance Registry System: 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-methyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide(935999-02-3)

Safety Data

• Hazardous Substances Data: 935999-02-3(Hazardous Substances Data)

Upstream product

• 1271949-52-0 5-chloro-pyridine-2-carboxylic acid (3-acetyl-4-fluoro-phenyl)-amide 
• 1271949-56-4 5-chloro-pyridine-2-carboxylic acid [3-((E)-3-carbamimidoylsulfanyl-1-methyl-propenyl)-4-fluoro-phenyl]-amide hydrochloride 
• 128073-03-0 4-chloronicotinoyl chloride 
• 67500-19-0 5'-Amino-2'-fluoroacetophenone 
• 1271949-54-2 5-chloro-pyridine-2-carboxylic acid [4-fluoro-3-(1-hydroxy-1-methyl-allyl)-phenyl]-amide 

Downstream Products

• 1271948-76-5 (S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-chloropicolinamide 
• 1271949-32-6 5-chloro-pyridine-2-carboxylic acid [3-((R)-2-amino-4-methyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide 

Relevant articles and documents

2 -AMINODIHYDRO [1, 3] THIAZINES AS BACE 2 INHIBITORS FOR THE TREATMENT OF DIABETES

This invention relates to the use of aminodihydrothiazines of the formula wherein R1 to R3 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof, and pharmaceutical compositions con