936011-17-5

Basic information

• Product Name: 5-broMo-2-Methoxyisonicotinaldehyde
• Synonyms: 5-broMo-2-Methoxyisonicotinaldehyde;5-Bromo-2-methoxypyridine-4-carboxaldehyde;5-Bromo-2-methoxy-pyridine-4-carbaldehyde
• CAS NO: 936011-17-5
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03204
• Mol File: 936011-17-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 273.596°C at 760 mmHg
• Flash Point: 119.267°C
• Appearance: /
• Density: 1.606g/cm³
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-broMo-2-Methoxyisonicotinaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-2-Methoxyisonicotinaldehyde(936011-17-5)
• EPA Substance Registry System: 5-broMo-2-Methoxyisonicotinaldehyde(936011-17-5)

Safety Data

• Hazardous Substances Data: 936011-17-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-methoxyisonicotinaldehyde is a chemical compound with the molecular formula C8H7BrNO2. It is a yellow to orange solid that is used in organic synthesis as a building block for pharmaceuticals and other biologically active compounds. Its unique structure and properties make it useful for the preparation of various derivatives and analogues for drug development and research. This chemical is also known for its high purity and stability, making it a valuable reagent in laboratory settings. Additionally, 5-Bromo-2-methoxyisonicotinaldehyde has potential applications in the field of medicinal chemistry and drug discovery due to its ability to interact with biological targets and modulate specific biological pathways.

InChI:InChI=1/C7H6BrNO2/c1-11-7-2-5(4-10)6(8)3-9-7/h2-4H,1H3

Upstream product

• 13472-85-0 2-methoxy-5-bromopyridine 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1060816-46-7 7-methoxy-1,2,3,4-tetrahydro-2,6-naphthyridine 
• 886365-25-9 methyl 5-bromo-2-methoxy-pyridine-4-carboxylate 
• 1227589-24-3 (5-bromo-2-methoxypyridine-4-yl)methanol 
• 1590407-03-6 C₁₉H₁₀F₄N₂O₂ 

Relevant articles and documents

Synthesis method of 4-(difluoromethyl)-2-hydroxypyridine-5-sulfonyl chloride

The invention provides a synthetic method of 4-(difluoromethyl)-2-hydroxypyridine-5-sulfonyl chloride, and belongs to the field of organic chemical synthesis. The synthetic method mainly comprises thefollowing steps: reacting a compound B with diethylamino sulfur trifluoride to obtain a compound C; reacting the compound C with sodium iodide and trimethylchlorosilane to obtain a compound D; reacting the compound D with benzyl mercaptan and 4, 5-diphenylphosphine-9, 9-dimethyl xanthene under the action of an alkali and a catalyst to obtain a compound E; and reacting the compound E with N-chlorosuccinimide to obtain a final product compound F. The method is high in selectivity, mild in reaction condition, simple in synthesis operation and easy to implement. In the synthesis process, the compound B is a self-made synthetic material, 5-bromo-2-methoxypyridine is used as a raw material, and nucleophilic substitution reaction is performed to obtain the compound B.

NOVEL TETRAHYDROISOQUINOLINES AND TERAHYDRONAPHTHYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The present invention provides novel compounds having the general formula (I): wherein R1, R 2, R 3, U, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.

INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING

The present application is directed to compounds of Formula I: compounds comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.