936095-23-7Relevant articles and documents
Synthesis and pharmacological characterization of N3-substituted willardiine derivatives: Role of the substituent at the 5-position of the uracil ring in the development of highly potent and selective GLUK5 kainate receptor antagonis
Dolman, Nigel P.,More, Julia C. A.,Alt, Andrew,Knauss, Jody L.,Pentik?inen, Olli T.,Glasser, Carla R.,Bleakman, David,Mayer, Mark L.,Collingridge, Graham L.,Jane, David E.
, p. 1558 - 1570 (2007/10/03)
Some N3-substituted analogues of willardiine such as 11 and 13 are selective kainate receptor antagonists. In an attempt to improve the potency and selectivity for kainate receptors, a range of analogues of 11 and 13 were synthesized with 5-sub