936128-54-0

Basic information

• Product Name: 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylic acid
• Synonyms: 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylic acid
• CAS NO: 936128-54-0
• Molecular Weight: 245.302
• Mol File: 936128-54-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylic acid(936128-54-0)
• EPA Substance Registry System: 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylic acid(936128-54-0)

Safety Data

• Hazardous Substances Data: 936128-54-0(Hazardous Substances Data)

Upstream product

• 32803-73-9 methyl 3-phenyl-3-chloro-2-ketopropionate 
• 100-52-7 benzaldehyde 
• 1038508-84-7 methyl 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylate 

Downstream Products

• 1258458-56-8 2-cyclopropyl-5-phenyl-thiazole-4-carboxylic acid [2-(3-acetyl-pyrazol-1-ylmethyl)-oxazol-4-yl]-amide 
• 1258459-41-4 [2-(3-acetyl-pyrazol-1-ylmethyl)-oxazol-4-yl]-(2-cyclopropyl-5-phenyl-thiazole-4-carbonyl)-carbamic acid tert-butyl ester 
• 1258458-99-9 2-cyclopropyl-5-phenyl-thiazole-4-carbonyl chloride 

Relevant articles and documents

SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

There is provided a compound of formula (I), wherein L1 to L3, R1 to R4, X, A and B have meanings given in the description, and pharmaceutically acceptable salts, solvates and prodrugs thereof, which compounds are useful as antagonists of the orexin-1 and orexin-2 receptors or as selective antagonists of the orexin-1 receptor, and thus, in particular, in the treatment or prevention of inter alia substance dependence, addiction, anxiety disorders, panic disorders, binge eating, compulsive disorders, impulse control disorders, cognitive impairment and Alzheimer's disease.

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES

The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS

The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R2, R3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.