93625-05-9

Basic information

• Product Name: carbomethoxy-2 methyl-3 p-methoxy phenoxymethyl-5 tetrahydrodioxazine-1,4,2
• Synonyms: carbomethoxy-2 methyl-3 p-methoxy phenoxymethyl-5 tetrahydrodioxazine-1,4,2
• CAS NO: 93625-05-9
• Molecular Weight: 297.308
• Mol File: 93625-05-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: carbomethoxy-2 methyl-3 p-methoxy phenoxymethyl-5 tetrahydrodioxazine-1,4,2(CAS DataBase Reference)
• NIST Chemistry Reference: carbomethoxy-2 methyl-3 p-methoxy phenoxymethyl-5 tetrahydrodioxazine-1,4,2(93625-05-9)
• EPA Substance Registry System: carbomethoxy-2 methyl-3 p-methoxy phenoxymethyl-5 tetrahydrodioxazine-1,4,2(93625-05-9)

Safety Data

• Hazardous Substances Data: 93625-05-9(Hazardous Substances Data)

Upstream product

• 105-57-7 diethyl acetal 
• 93624-87-4 α-p-methoxy phenoxymethyl β-N-carbomethoxy aminoxyethanol 
• 2211-94-1 2,3-epoxypropyl p-methoxyphenyl ether 

Relevant articles and documents

Ouverture d'epoxydes par le N-hydroxycarbamates de methyle; syntheses de tetrahydrodioxazine-1,4,2 ones-3 et de carbomethoxy-2 tetrahydrodioxazines-1,4,2

The ring opening of epoxides in a basic medium by methyl N-hydroxycarbamate reacting as an N-protected hydroxylamine by its oxanion CH3O-CO-NHO(-) gives the corresponding carbomethoxyaminoxyalcohols 2.These compounds can react further to give: N,O-di(hydroxy-2' alkyl)hydroxylamines 3 by opening of a second epoxide molecule; diols RCH(OH)CH2OH 4 by rupture in basic medium of the N-O linkage of 2; 1,4,2-tetrahydrodioxazine-3 ones 5 by intramolecular cyclisation of 2.The oxanion CH3O-CO-NHO(-) attacks the primary carbon of the epoxide except in the case of epoxystyrene where as minor attack on the secondary carbon is also observed.The cyclization of carbomethoxyaminoxyalcohols 2 with aldehydes or their corresponding acetals in the presence of paratoluene sulfonic acid is a rapid and easy two step synthesis of 2-carbomethoxy-tetrahydrodioxazines-1,4,2 8.