936330-65-3Relevant academic research and scientific papers
Synthesis and evaluation of (1S)-1,2-dihydro-1-naphthalenol derivatives against PANC-1 cells
Zhang, Hong,Kartub, Kellen,Kwan, Alice,Webb, Andrew,Carrico-Moniz, Dora
, p. 1720 - 1723 (2015/03/14)
Several derivatives of (1S)-1,2-dihydro-1-naphthalenol ((S)-7) have been synthesized and evaluated against human pancreatic adenocarcinoma cell line PANC-1 under nutrient-rich and nutrient-deprived conditions. The tert-butyldiphenylsilyl protected homoall
A catalytic asymmetric entry to enantioenriched tertiary naphthoquinols via a facile tandem oxidation/ring-opening sequence
Kwan, Alice,Stein, Johanna,Carrico-Moniz, Dora
supporting information; experimental part, p. 3426 - 3428 (2011/06/27)
The tertiary naphthoquinol is a key structural component of the antitumor natural products spiroxins A-E. Herein we report the first catalytic asymmetric approach to the tertiary naphthoquinol C4′ stereogenic center present in the spiroxin framework, via
Synthesis of daunorubicin analogues containing truncated aromatic cores and unnatural monosaccharide residues
Fan, Eric,Shi, Wei,Lowary, Todd L.
, p. 2917 - 2928 (2008/02/01)
(Chemical Equation Presented) The anthracycline antibiotics daunorubicin and doxorubicin have been used widely as anticancer drugs, but their cardiotoxicity limits their clinical use. We describe here the preparation of a small panel of daunorubicin analo
