936371-73-2Relevant academic research and scientific papers
Ruthenium-catalyzed cycloisomerization-6π-cyclization: A novel route to pyridines
Trost, Barry M.,Gutierrez, Alicia C.
, p. 1473 - 1476 (2007)
Equation presented Herein we report a method for the synthesis of substituted pyridines. The unsaturated ketones and aldehydes derived from the cycloisomerization of primary and secondary propargyl diynols in the presence of [CpRu (CH3CN)3
Gold(I)-catalyzed cycloisomerization of 1,6-diynes: Synthesis of 2,3-disubstituted 3-pyrroline derivatives
Zhang, Di-Han,Yao, Liang-Feng,Wei, Yin,Shi, Min
, p. 2583 - 2587 (2011/04/27)
A novel synthetic protocol for the preparation of the title compounds has been developed from a gold-catalyzed cycloisomerization of 1,6-diynes containing propargylic ester and arene-yne units. The corresponding nitrogen-containing five-membered heterocyclic compounds have been obtained in moderate to good yields (see scheme; DCE=1,2-dichloroethane, Tf=triflate). A plausible reaction mechanism has been proposed on the basis of deuterium labeling experiments. Copyright
