936482-53-0Relevant articles and documents
Discovery and structure - Activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors
Pei, Zhonghua,Li, Xiaofeng,Von Geldern, Thomas W.,Longenecker, Kenton,Pireh, Daisy,Stewart, Kent D.,Backes, Bradley J.,Lai, Chunqiu,Lubben, Thomas H.,Ballaron, Stephen J.,Beno, David W. A.,Kempf-Grote, Anita J.,Sham, Hing L.,Trevillyan, James M.
, p. 1983 - 1987 (2008/02/04)
Dipeptidyl peptidase IV (DPP4) inhibitors are emerging as a new class of therapeutic agents for the treatment of type 2 diabetes. They exert their beneficial effects by increasing the levels of active glucagon-like peptide-1 and glucose-dependent insulino