936495-28-2

Upstream product

• 936494-95-0 tert-Butyl-dimethyl-((3S,4S,5S,6S)-3,5,7-tris-benzyloxy-4,6-dimethyl-heptyloxy)-silane 
• 936495-24-8 Toluene-4-sulfonic acid (2R,3S,4S,5S)-4,6-bis-benzyloxy-2-hydroxy-3,5-dimethyl-hexyl ester 
• 936494-93-8 2-((2S,3S,4S,5S)-2,4,6-Tris-benzyloxy-3,5-dimethyl-hexyl)-[1,3]dithiane 
• 936494-92-7 (2S,3S,4S,5S)-4,6-Bis-benzyloxy-1-[1,3]dithian-2-yl-3,5-dimethyl-hexan-2-ol 
• 936494-94-9 (3S,4S,5S,6S)-3,5,7-Tris-benzyloxy-4,6-dimethyl-heptanal 
• 158661-80-4 (3S,4S,5S,6S)-3,5,7-Tris-benzyloxy-4,6-dimethyl-heptan-1-ol 
• 158661-82-6 {2-[(4S,5S,6R)-6-((R)-2-Benzenesulfonyl-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-ethoxy}-tert-butyl-dimethyl-silane 
• 936494-98-3 2,2-Dimethyl-propionic acid (S)-2-{(4S,5S,6S)-6-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propyl ester 
• 936494-90-5 (R)-4-((1R,2S,3S)-2,4-Bis-benzyloxy-1,3-dimethyl-butyl)-2,2-dimethyl-[1,3]dioxolane 
• 936494-99-4 tert-Butyl-dimethyl-{2-[(4S,5S,6R)-2,2,5-trimethyl-6-((R)-1-methyl-2-phenylsulfanyl-ethyl)-[1,3]dioxan-4-yl]-ethoxy}-silane 
• 936494-91-6 (2R,3S,4S,5S)-4,6-Bis-benzyloxy-3,5-dimethyl-hexane-1,2-diol 
• 158661-79-1 (R)-2-((1R,2S,3S)-2,4-Bis-benzyloxy-1,3-dimethyl-butyl)-oxirane 
• 936494-97-2 2,2-Dimethyl-propionic acid (2S,3S,4S,5S)-7-(tert-butyl-dimethyl-silanyloxy)-3,5-dihydroxy-2,4-dimethyl-heptyl ester 
• 158661-81-5 (S)-2-{(4S,5S,6S)-6-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propan-1-ol 

Downstream Products

• 936495-29-3 {2-[(4S,5S,6S)-6-((1S,4S,5S)-5-Benzyloxy-4-methoxy-1-methyl-hexyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-ethoxy}-tert-butyl-dimethyl-silane 
• 936495-31-7 2-[(4S,5S,6S)-6-((1S,4S,5S)-5-Benzyloxy-4-methoxy-1-methyl-hexyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-ethanol 
• 936495-35-1 C₃₁H₄₂Br₂N₂O₇ 

Relevant academic research and scientific papers

Aplyronine A, a potent antitumor macrolide of marine origin, and the congeners aplyronines B and C: isolation, structures, and bioactivities

Aplyronine A (2), a potent antitumor macrolide was isolated from the sea hare Aplysia kurodai together with the congeners aplyronines B (3) and C (4). The absolute stereostructure of aplyronine A (2) was determined by the instrumental analysis (mainly NMR and MS) and the enantioselective synthesis of the fragments obtained from chemical degradation of aplyronine A (2). The structures of aplyronines B (3) and C (4) were also elucidated. Cytotoxicity and antitumor activity of aplyronine A (2) were evaluated.