936495-41-9

Upstream product

• 186581-53-3 diazomethane 
• 936495-40-8 (2S,4R)-1,6-Bis-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hexan-2-ol 
• 7540-51-4 (S)-3,7-dimethyl-6-octen-1-ol 
• 2111-53-7 (S)-(-)-citronellic acid 
• 56994-89-9 (S)-(-)-citronellic acid,methyl ester 
• 158661-88-2 (4S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-4-methyl-tetrahydro-pyran-2-one 
• 936495-38-4 (2S,4R)-4-Methyl-hexane-1,2,6-triol 
• 158661-85-9 (S)-3-Methyl-6-(2-nitro-phenylselanyl)-hexanoic acid methyl ester 
• 158661-84-8 methyl (S)-6-hydroxy-3-methylhexanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Relevant academic research and scientific papers

Aplyronine A, a potent antitumor macrolide of marine origin, and the congeners aplyronines B and C: isolation, structures, and bioactivities

Aplyronine A (2), a potent antitumor macrolide was isolated from the sea hare Aplysia kurodai together with the congeners aplyronines B (3) and C (4). The absolute stereostructure of aplyronine A (2) was determined by the instrumental analysis (mainly NMR and MS) and the enantioselective synthesis of the fragments obtained from chemical degradation of aplyronine A (2). The structures of aplyronines B (3) and C (4) were also elucidated. Cytotoxicity and antitumor activity of aplyronine A (2) were evaluated.