936502-07-7Relevant academic research and scientific papers
Exceptional stereoselectivity in the synthesis of 1,3,4-trisubstituted 4-carboxy β-lactam derivatives from amino acids
Perez-Faginas, Paula,O'Reilly, Fran,O'Byrne, Aisling,Garcia-Aparicio, Carlos,Martin-Martinez, Mercedes,De Jesus Perez Vega,Teresa Garcia-Lopez,Gonzalez-Muniz, Rosario
, p. 1593 - 1596 (2008/02/02)
Equation presented The base-promoted cyclization of optically pure N-(p-methoxybenzyl)-N-(2-chloro)propionyl amino acid derivatives resulted in a diastereo- and enantioselective approach to valuable 1,3,4,4-tetrasubstituted β-lactams. The stereochemical outcome of the reaction is exclusively governed by the configuration of the N-(2-chloro)propionyl moiety.
