93652-35-8Relevant academic research and scientific papers
Stilbene synthesis through decarboxylative cross-coupling of substituted cinnamic acids with aryl halides
Rameau, Nelly,Russo, Baptiste,Mangematin, Stéphane,Pinel, Catherine,Djakovitch, Laurent
, p. 132 - 143 (2018/05/22)
The Pd-catalyzed decarboxylative cross-coupling reaction between cinnamic acid and aryl iodide derivatives was studied using both homogeneous and heterogeneous Pd-catalysts. It was demonstrated that simple Pd(OAc)2 can catalyze this reaction wi
Synthesis of 1,1-diarylethylenes
Chang, Meng-Yang,Huang, Yi-Hsuan,Wang, Heui-Sin
, p. 3022 - 3031 (2016/05/19)
A facile route toward 1,1-diarylethylenes 6 has been developed in good yields via mCPBA-promoted oxidation of β-hydroxysulfides 2, BF3·OEt2-mediated Friedel-Crafts reaction of the resulting β-hydroxysulfoxides 3 with oxygenated benze
Synthesis of methylated resveratrol and analogues by Heck reactions in organic and aqueous solvents
Botella, Luis,Nájera, Carmen
, p. 5563 - 5570 (2007/10/03)
The Heck reaction under phosphane free conditions using oxime-derived palladacycles or Pd(OAc)2 as catalysts is a general methodology for the synthesis of methoxylated (E)-stilbene derivatives. Couplings can be performed either with (dicyclohexyl)methylamine as base and TBAB in aqueous DMA or in neat water and with Et3N as base in DMA in air and under thermal and microwave conditions. The arylation of different styrenes are performed with 3,5-dimethoxyiodobenzene to afford a series of important biologically active (E)-stilbene derivatives containing the 3,5-dimethoxyphenyl moiety, including resveratrol, piceatannol and pinosilvine, which are efficiently prepared with high regioselectivity and total stereoselectivity (TON up to 104).
