936635-85-7

Upstream product

• 936635-84-6 methyl 4-(1-methyl-4-oxo-1,4-dihydropyridin-3-yl)benzoate 
• 87875-77-2 3-bromo-1-methyl-4-pyridone hydrobromide salt 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 

Downstream Products

• 936635-76-6 N-(5-chloropyridin-2-yl)-3-hydroxy-2-{[4-(1-methyl-4-oxo-1,4-dihydropyridin-3-yl)benzoyl]amino}benzamide 

Relevant academic research and scientific papers

BENZENE DERIVATIVE OR SALT THEREOF

Problem: To provide compounds which have an anticoagulation effect based on their ability to inhibit the activated blood coagulation factor X and are useful as coagulation inhibitors or agents for prevention or treatment for diseases caused by thrombi or emboli. Means for Solution: Benzene derivatives or their salts having a characteristic chemical structure with a phenol ring and a benzene ring bonding to each other via an amide bond, in which the phenol ring further bonds to a benzene ring or a heteroaryl ring via an amide bond. They have an excellent effect of inhibiting the activated blood coagulation factor X, and especially have an excellent oral activity.