93677-03-3Relevant articles and documents
Hydrogen Peroxide Promoted Mizoroki-Heck Reactions of Phenyldiazenes with Acrylates, Acrylamides, and Styrenes
Lasch, Roman,Fehler, Stefanie K.,Heinrich, Markus R.
supporting information, p. 1586 - 1589 (2016/05/02)
Mizoroki-Heck reactions, which are well-known for aryldiazonium salts and which have recently been described for arylhydrazines, have now been extended to phenyldiazenes. In situ generation of phenyldiazenes from azocarboxylates allowed clean and selective reactions with styrenes, acrylates, and acrylamides using palladium(II) acetate in the presence of silver(I) acetate or hydrogen peroxide as oxidant. Hydrogen peroxide was thereby shown to be a cheap and broadly applicable alternative for the established palladium-silver(I) system.
Heck reactions using segmented flow conditions
Ahmed-Omer, Batoul,Barrow, David A.,Wirth, Thomas
experimental part, p. 3352 - 3355 (2009/08/17)
Various Heck couplings have been carried out using segmented flow conditions to accelerate the reactions. Aryl iodides and aryl bromides as well as anilines in diazonium-type Heck reactions have been used successfully.
Total Synthesis of Combretastatin D-2: Intramolecular Ullmann Macrocyclization Reaction
Boger, Dale L.,Sakya, Subas M.,Yohannes, Daniel
, p. 4204 - 4207 (2007/10/02)
The total synthesis of combretastatin D-2, a cytotoxic constituent of Combretum caffrum (Combretaceae), is detailed and is based on the implementation of a key intramolecular Ullmann macrocyclization reaction for formation of the cyclic 15-membered caffra