93681-81-3Relevant academic research and scientific papers
Intramolecular Reactions of N-Nitrenes with Alkenes
Atkinson, Robert S.,Malpass, John R.,Skinner, Karen L.,Woodthorpe, Katherine L.
, p. 1905 - 1912 (2007/10/02)
Oxidation of 2-but-1-enyl- and 2-(1-phenylbut-1-enyl)-3-aminoquinazolin-4(3H)-ones (8) and (10), respectively, generates the corresponding N-nitrenes which are trapped intramolecularly by the double bonds.The results from competitive intramolecular trapping of the N-nitrene by different double bonds in 3-aminoquinazolones bearing bifurcated chains in position 2 indicate that these intramolecular nitrene additions are non-concerted and, as in the corresponding intramolecular addition to aromatic rings, proceed via 7-membered transition states with the nitrene functioning as an electrophile.
