936835-57-3

Upstream product

• 106-37-6 1.4-dibromobenzene 
• 130222-84-3 5-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribono-1,4-lactone 
• 179762-64-2 1-(4-bromophenyl)-5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose 
• 936836-28-1 [6-allyl-6-(4-bromo-phenyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-tert-butyl-diphenyl-silane 

Downstream Products

• 881424-04-0 acetic acid 5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,2-b]furan-3-yl ester 
• 881423-95-6 acetic acid 6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester 
• 881423-96-7 1-[(1R,3S,5S,7R,8R)-5-(4-bromophenyl)-8-hydroxy-7-(hydroxymethyl)-2,6-dioxabicyclo[3.3.0]octan-3-yl]thymine 
• 881423-78-5 (1R,5S,7R,8R)-5-(4-bromophenyl)-7-[(tert-butyldiphenylsilyloxy)methyl]-2,6-dioxabicyclo[3.3.0]octane-3,8-diyl diacetate 

Relevant academic research and scientific papers

Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes

Triplex-forming oligonucleotides (TFOs) are sequence-specific DNA-binding agents, but their target duplexes are limited to homopurine/homopyrimidine sequences because of interruption of the pyrimidines bases in the purine region. This problem has not been