936844-19-8Relevant articles and documents
Synthesis and biological evaluation of GPR40/FFAR1 agonists containing 3,5-dimethylisoxazole
Yang, Lingyun,Zhang, Jian,Si, Lianghui,Han, Li,Zhang, Bo,Ma, Hui,Xing, Junhao,Zhao, Leilei,Zhou, Jinpei,Zhang, Huibin
, p. 46 - 58 (2016/04/19)
GPR40 is an attractive target due to its glucose-stimulated insulin secretion effect with low risk of causing hypoglycemia, which also can be seen from the clinical studies using TAK-875 (fasiglifam). In the present studies, we discovered a series of anal