936846-45-6Relevant articles and documents
The discovery of potent and selective 4-aminothienopyridines as B-Raf kinase inhibitors
Tang, Jun,Lackey, Karen E.,Dickerson, Scott H.
, p. 66 - 70 (2013)
A series of novel, potent 4-aminothienopyridine B-Raf kinase inhibitors was designed and synthesized using knowledge-based design. Compounds 5f, and 6k exhibited not only excellent potency in both enzyme assay (IC50 = 5.1, 16.6 nM) and cellular
THIENOPYRIDINE B-RAF KINASE INHIBITORS
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Page/Page column 36-37, (2008/06/13)
The present invention provides thienopyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.