799293-91-7

Usage

Uses

Used in Synthetic Chemistry:
3-bromo-7-iodo-Thieno[3,2-c]pyridin-4-amine is used as a building block in synthetic chemistry for the creation of more complex organic molecules. Its unique structure, which includes both bromine and iodine atoms, allows for versatile synthetic pathways and the potential to form a variety of novel compounds.
Used in Pharmaceutical Research:
As a potential drug candidate, 3-bromo-7-iodo-Thieno[3,2-c]pyridin-4-amine is utilized in pharmaceutical research for the development of new therapeutic agents. Its specific biological activity and potential applications are yet to be fully explored, but the compound's unique chemical structure suggests it may have interesting properties for medicinal chemistry and drug discovery efforts.

Upstream product

• 799293-85-9 3-bromo-4-amino-[3,2-c]-thienopyridine 
• 18791-75-8 4-Bromothiophen-2-aldehyde 
• 799293-88-2 3-bromo-7-iodothieno[3,2-c]pyridin-4(5H)-one 
• 799293-81-5 trans-3-(4-bromothiophen-2-yl)-acryloyl azide 
• 29064-82-2 3-bromo-4-chloro-[3,2-c]-thienopyridine 
• 799293-83-7 3-bromothieno[3,2-c]pyridin-4(5H)-one 
• 799293-89-3 3-bromo-4-chloro-7-iodo-thieno[3,2-c]pyridine 
• 103686-16-4 trans-3-(4-bromothiophen-2-yl)propenoic acid 

Downstream Products

• 936846-59-2 3-(3-aminophenyl)-7-(3-pyridinyl)thieno[3,2-c]pyridin-4-amine 
• 1416909-24-4 C₂₄H₁₈N₄O₂S₂ 
• 1416909-26-6 C₂₄H₁₉N₅OS 

Relevant academic research and scientific papers

Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2-c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases

A novel class of 3,7-diphenyl-4-amino-thieno and furo[3,2-c]pyridine has been designed based on pharmacophore models of ATP competitive kinase inhibitors. Versatile synthetic methods via double Suzuki coupling to explore SAR have been established and potent inhibitors against angiogenetic targets, VEGFR2, Tie-2, and EphB4, have been successfully discovered.

Discovery of thienopyridines as Src-family selective Lck inhibitors

We describe the identification, SAR, and in vivo pharmacology of a new series of Src-family selective Lck inhibitors. These thienopyridines were designed based on a desire to access the unique residues in the extended hinge region of Lck.

Inhibitors of protein kinases

Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

KINASE INHIBITORS AS THERAPEUTIC AGENTS

A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.

Thienopyridine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Thienopyridine and furopyridine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

NOVEL CHEMICAL COMPOUNDS

This invention relates to newly identified compounds for treating and preventing tumors ans cancers, and methods for treating proliferative diseases associated with the imbalance or inappropriate activity of tyrosine kinases implicated in proliferative diseases.