936846-56-9

Upstream product

• 936846-59-2 3-(3-aminophenyl)-7-(3-pyridinyl)thieno[3,2-c]pyridin-4-amine 
• 131825-41-7 3,5-dimethylisoxazol4-yl isocyanate 
• 799293-91-7 3-bromo-7-iodothieno[3,2-c]pyridin-4-amine 

Relevant academic research and scientific papers

The discovery of potent and selective 4-aminothienopyridines as B-Raf kinase inhibitors

A series of novel, potent 4-aminothienopyridine B-Raf kinase inhibitors was designed and synthesized using knowledge-based design. Compounds 5f, and 6k exhibited not only excellent potency in both enzyme assay (IC50 = 5.1, 16.6 nM) and cellular

THIENOPYRIDINE B-RAF KINASE INHIBITORS

The present invention provides thienopyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.