936941-76-3Relevant academic research and scientific papers
Tandem alkylation - Michael addition to vinylogous carbonates for the stereoselective construction of 2,3,3,6-tetrasubstituted tetrahydropyrans
Gharpure, Santosh J.,Reddy, S. Raja Bhushan
supporting information; scheme or table, p. 2519 - 2522 (2009/10/18)
A stereoselective method for the synthesis of substituted tetrahydropyran derivatives employing a tandem SN2-Michael addition sequence to vinylogous carbonates is developed. The method is extended to the synthesis of bicyclic ether motifs present in polyether ladder toxins.
