937-18-8

Usage

Methyl ester derivative

1H-pyrrole-2-carboxylic acid The compound is derived from 1H-pyrrole-2-carboxylic acid by replacing the hydroxyl group (-OH) with a methyl group (-CH3).

Contains a cyano group

-CN The molecule has a cyano group (C≡N) attached to the pyrrole ring, which contributes to its reactivity and potential applications in organic synthesis.

Potential applications

Medicinal chemistry and organic synthesis The compound has potential uses in the development of pharmaceuticals, agrochemicals, and other biologically active compounds, making it a valuable building block in these fields.

Precursor in synthesis

Pharmaceutical, agrochemical, and biologically active compounds 1H-Pyrrole-2-carboxylic acid, 4-cyano-, methyl ester (9CI) can be used as a starting material or precursor in the synthesis of various compounds, including those with pharmaceutical, agrochemical, and biological activity.

Safety precautions

Handle with care and follow safety guidelines Due to potential health risks, it is important to handle this chemical with care and follow appropriate safety guidelines to minimize exposure and ensure safe handling.

Upstream product

• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 1189-71-5 isocyanate de chlorosulfonyle 

Downstream Products

• 86289-03-4 3-(4-Chloro-phenyl)-1-oxo-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-7-carbonitrile 
• 66491-00-7 Methyl 4-cyano-1-(2-phenethyl)pyrrole-2-carboxylate 
• 62541-79-1 Methyl N-Phenacyl-4-cyano-pyrrole-2-carboxylate 
• 86307-71-3 1-[2-(4-Chloro-phenyl)-2-oxo-ethyl]-4-cyano-1H-pyrrole-2-carboxylic acid methyl ester 
• 65561-21-9 N-(E)-Styryl-4-cyanopyrrole-2-carboxylic Acid 
• 66491-01-8 4-Cyano-1-(2-phenethyl)pyrrole-2-carboxylic Acid 
• 65561-23-1 N-(E)-Styryl-4-cyano-2-(chlorocarbonyl)pyrrole 
• 65561-22-0 N-(Z)-Styryl-4-cyanopyrrole-2-carboxylic Acid 
• 86289-04-5 4-Cyano-1-((Z)-styryl)-1H-pyrrole-2-carbonyl chloride 
• 86289-17-0 Sodium N-(2-Hydroxyphenethyl)-4-cyanopyrrole-2-carboxylate 
• 65561-24-2 N-(1,2-Dichlorophenethyl)-4-cyano-2-(chlorocarbonyl)pyrrole 
• 65561-26-4 7-Cyano-3,4-dihydro-1-oxo-3-phenyl-1H-pyrrolo<1,2-c>morpholine 

Relevant academic research and scientific papers

PYRRO[1,2-B]PYRIDAZINONE COMPOUNDS

The invention is directed to pyrro[l,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Pyrrole chemistry. XXIII. The cyanation of substituted pyrroles with chlorosulfonyl isocyanate (CSI). New syntheses of pyrrole-3-carbonitriles

Chlorosulfonyl isocyanate (CSI) reacts not only with pyrrole itself but with pyrroles having powerful electron-withdrawing groups in the 2-position.Suitable choice of electron-withdrawing groups allows selective 4-substitution of the pyrrole ring.The N-chlorosulfonyl amides formed are readily converted to the corresponding nitriles.The procedure has been used to provide syntheses of pyrrole-3-carbonitrile and its 1-methyl homologue.