Methyl 4-cyano-1H-pyrrole-2-carboxylate

Base Information

Chemical Name:Methyl 4-cyano-1H-pyrrole-2-carboxylate
CAS No.:937-18-8
Molecular Formula:C7H6 N2 O2
Molecular Weight:150.13
Hs Code.:2933990090
European Community (EC) Number:822-603-5
DSSTox Substance ID:DTXSID60450749
Wikidata:Q82270560
Mol file:937-18-8.mol

Synonyms:Methyl 4-cyano-1H-pyrrole-2-carboxylate;937-18-8;4-CYANO-1H-PYRROLE-2-CARBOXYLIC ACID METHYL ESTER;1H-Pyrrole-2-carboxylic acid, 4-cyano-, methyl ester;SCHEMBL3766521;DTXSID60450749;KLLCRUMWQRYULP-UHFFFAOYSA-N;AKOS022060340;SB62453;Methyl4-cyano-1H-pyrrole-2-carboxylate;BS-51031;CS-0343314;FT-0733958;EN300-1710094;Z1255380431

Suppliers and Price of Methyl 4-cyano-1H-pyrrole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4-cyano-1H-pyrrole-2-carboxylate 97%
5g
$ 1240.00

Crysdot
Methyl4-cyano-1H-pyrrole-2-carboxylate 97%
1g
$ 545.00

Crysdot
Methyl4-cyano-1H-pyrrole-2-carboxylate 97%
10g
$ 1736.00

Alichem
Methyl4-cyano-1H-pyrrole-2-carboxylate
5g
$ 1302.48

Alichem
Methyl4-cyano-1H-pyrrole-2-carboxylate
25g
$ 2898.42

Alichem
Methyl4-cyano-1H-pyrrole-2-carboxylate
10g
$ 1894.76

AccelPharmtech
4-cyano-1H-Pyrrole-2-carboxylicacidmethylester 97.00%
25G
$ 13300.00

AccelPharmtech
4-cyano-1H-Pyrrole-2-carboxylicacidmethylester 97.00%
1G
$ 3120.00

Total 8 raw suppliers

Chemical Property of Methyl 4-cyano-1H-pyrrole-2-carboxylate

Chemical Property:

PSA：65.88000
LogP:0.67298
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:150.042927438
Heavy Atom Count:11
Complexity:206

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-cyano-1H-pyrrole-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=CN1)C#N

Technology Process of Methyl 4-cyano-1H-pyrrole-2-carboxylate

There total 3 articles about Methyl 4-cyano-1H-pyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.4%

: 1193-62-0
methyl Pyrrole-2-carboxylate

: 1189-71-5
isocyanate de chlorosulfonyle

: 937-18-8
methyl 4-cyanopyrrole-2-carboxylate

Guidance literature:: In acetonitrile; at -20 - 25 ℃; for 20.0833h;

Reference yield:

: 1193-62-0
methyl Pyrrole-2-carboxylate

: 1189-71-5
isocyanate de chlorosulfonyle

: 937-18-8
methyl 4-cyanopyrrole-2-carboxylate

: 937-19-9
5-cyano-1H-pyrrole-2-carboxylic acid methyl ester

Guidance literature:: With N,N-dimethyl-formamide; Yield given. Multistep reaction; 1.) acetonitrile, ice bath, 5 min, room temp., overnight; 2.) ice bath then 50 deg C, 15 min;