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2-(2-Amino-6-chloro-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol, also known as GS-441524, is a nucleoside analog with antiviral properties. It has demonstrated the ability to inhibit the replication of specific RNA viruses, including coronaviruses such as SARS-CoV-2. GS-441524 functions by disrupting viral RNA synthesis, making it a promising candidate for the treatment of COVID-19 and other viral infections.

937031-52-2

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937031-52-2 Usage

Uses

Used in Antiviral Applications:
2-(2-Amino-6-chloro-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol is used as an antiviral agent for its ability to inhibit the replication of certain RNA viruses. It is particularly effective against coronaviruses like SARS-CoV-2, where it interferes with viral RNA synthesis, thereby preventing the spread of the virus within the host.
Used in COVID-19 Treatment:
In the healthcare industry, 2-(2-Amino-6-chloro-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol is being investigated as a potential treatment for COVID-19. Its antiviral activity has shown promising results in preclinical studies, and it is currently undergoing clinical trials to assess its efficacy and safety in treating patients with the disease.
Used in Pharmaceutical Research and Development:
2-(2-Amino-6-chloro-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol is utilized in the pharmaceutical industry for research and development of new antiviral drugs. Its unique mechanism of action and potential to treat a range of viral infections make it a valuable compound for further exploration and development into effective therapeutic options.

Check Digit Verification of cas no

The CAS Registry Mumber 937031-52-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,7,0,3 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 937031-52:
(8*9)+(7*3)+(6*7)+(5*0)+(4*3)+(3*1)+(2*5)+(1*2)=162
162 % 10 = 2
So 937031-52-2 is a valid CAS Registry Number.

937031-52-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name D-Altritol, 2-(4-amino-5-methyl-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-

1.2 Other means of identification

Product number -
Other names 2-(2-amino-6-chloro-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-Altritol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:937031-52-2 SDS

937031-52-2Relevant academic research and scientific papers

Fmoc-protected altritol phosphoramidite building blocks and their application in the synthesis of altritol nucleic acids (ANAs)

Abramov, Mikhail,Schepers, Guy,Van Aerschot, Arthur,Herdewijn, Piet

, p. 1446 - 1456 (2008/09/18)

Fmoc-protected altritol nucleoside phosphoramidite building blocks with adenine, guanine, thymine, uracil, cytosine and 5-methylcytosine as bases have been synthesized. These building blocks were used for the synthesis of altritol nucleic acid (ANA) and c

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