937369-77-2

Usage

Uses

Used in Chemical Synthesis:
5-phenylthiazole-2-carboxylic acid is used as a building block in the synthesis of various organic compounds due to its reactive phenyl and thiazole groups, which can participate in a range of chemical reactions.
Used in Pharmaceutical Research:
5-phenylthiazole-2-carboxylic acid is used as a research compound in the development of new pharmaceuticals, particularly in the field of medicine. Its unique structure may contribute to the discovery of novel drug candidates with potential therapeutic applications.
Used in Electrochemistry:
5-phenylthiazole-2-carboxylic acid is used as a component in electrochemical systems, where its properties may be exploited for the development of new electrochemical devices or materials, such as sensors or energy storage systems.
Used in Material Science:
5-phenylthiazole-2-carboxylic acid is used as a precursor in the synthesis of new materials with potential applications in various industries, such as electronics or coatings, due to its ability to form stable complexes with other molecules.
Used in Toxicological Studies:
5-phenylthiazole-2-carboxylic acid is used as a test compound in toxicological research to better understand its safety profile and potential health risks, which is essential for its safe handling and potential applications in various fields.

InChI:InChI=1/C10H7NO2S/c12-10(13)9-11-6-8(14-9)7-4-2-1-3-5-7/h1-6H,(H,12,13)

Upstream product

• 957346-62-2 5-bromo-1,3-thiazole-2-carboxylic acid 
• 98-80-6 phenylboronic acid 
• 58333-72-5 ethyl 5-phenyl-1,3-thiazole-2-carboxylate 
• 84978-66-5 ethyl 2-oxo-2-((2-oxo-2-phenylethyl)amino)acetate 
• 613-89-8 2-Aminoacetophenone 

Relevant academic research and scientific papers

INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 30

The present disclosure relates to chemical entities useful as inhibitors of Ubiquitin Specific Peptidase 30 (USP30), pharmaceutical compositions comprising the chemical entities, and methods of using the chemical entities. The chemical entities as disclosed herein can be useful in the treatment of a disease, disorder, or condition involving mitochondrial dysfunction, including neurodegenerative diseases, motor neuron diseases, metabolic disorders, and cancers, among other ailments.

FIVE-MEMBERED HETEROCYCLIC AMIDES WNT PATHWAY INHIBITOR

The present invention discloses a five-membered heterocyclic amide WNT pathway inhibitor, which belongs to a compound that regulates the activity of a Wnt signaling pathway, and provides a method for preparing such a compound, and the use of such a compound in preparing a medicament that antagonizes the Wnt signaling pathway. The five-membered heterocyclic amide WNT pathway inhibitor provided by the invention has a remarkable anti-tumor activity based on a target-based rational drug design of, and can be used for the development of a new generation of Wnt pathway inhibitors, and has a great clinical application value and considerable market potential.

NOVEL COMPOUNDS

The present invention relates to substituted N-(phenyl-heteroaryl)-3-acetylamino-benzamides and N- [3-(acetylamino)phenyl]-phenyl-heteroaryl-carboxamides of general formula(I) as described and defined herein,to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease.