937591-69-0

Usage

Uses

Used in Organic Chemistry Research:
2,3-Dihydrobenzofuran-5-boronic acid pinacol ester is used as a reagent in organic chemistry for its unique properties that facilitate Suzuki coupling reactions. These reactions are palladium-catalyzed cross-coupling processes that enable the formation of carbon-carbon bonds, which are fundamental in constructing complex organic molecules.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2,3-Dihydrobenzofuran-5-boronic acid pinacol ester is utilized as a key intermediate in the synthesis of various drug molecules. Its ability to participate in Suzuki coupling reactions allows for the creation of diverse molecular structures with potential therapeutic applications.
Used in Agrochemical Development:
Similarly, in agrochemicals, 2,3-Dihydrobenzofuran-5-boronic acid pinacol ester serves as a vital building block for the synthesis of compounds with pesticidal or herbicidal properties. Its role in forming carbon-carbon bonds through Suzuki coupling is essential for the development of new and effective agrochemicals.
Overall, 2,3-Dihydrobenzofuran-5-boronic acid pinacol ester is a versatile and indispensable compound in the realms of scientific research and chemical synthesis, particularly for the advancement of pharmaceuticals and agrochemicals.

Upstream product

• 66826-78-6 5-bromo-2,3-dihydrobenzo[b]furan 
• 73183-34-3 bis(pinacol)diborane 
• 519054-55-8 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran 
• 23145-07-5 5-bromobenzofuran 

Downstream Products

• 76429-68-0 5-methyl-2,3-dihydrobenzofuran 

Relevant academic research and scientific papers

MLL1 INHIBITORS AND ANTI-CANCER AGENTS

The present invention provides a compound of Formula (I): or an enantiomer, an enantiomeric mixture, or a pharmaceutically acceptable salt thereof; wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating a disease or condition mediated by mixed lineage leukemia 1 (MLL).

PYRIMIDINE SULFAMIDE DERIVATIVE AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF

Disclosed are a series of pyrimidine sulfamide compounds and applications thereof in preparing a drug for a disease related to an ETA receptor antagonist. In particular, disclosed is a derived compound represented by formula (I) or a tautomer or pharmaceutically acceptable composition thereof.

NEW COMPOUNDS

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

Imidazole derivatives

Novel imidazole derivatives are disclosed. These compounds have a good affinity to the NMDA (N-methyl-D-aspartate)-receptor subtype selective blockers, which have a key function in modulating neuronal activity and plasticity which makes them key players in mediating processes underlying development of CNS as well as learning and memory formation. These compounds are useful in the control or treatment of diseases mediated by this receptor.