937592-90-0

Upstream product

• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 214760-35-7 methanesulfonic acid 3-chloro-5-methoxy-phenyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 906008-22-8 3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1035267-57-2 5'-[2-amino-1-methyl-5-oxo-4-(tetrahydro-2H-pyran-4-yl)-4,5-dihydro-1H-imidazol-4-yl]-2'-fluoro-5-methoxybiphenyl-3-yl methanesulfonate hydrochloride 
• 1035266-48-8 5'-(2-amino-1-methyl-5-oxo-4-phenyl-4,5-dihydro-1H-imidazol-4-yl)-2'-fluoro-5-methoxybiphenyl-3-yl methanesulfonate 
• 1035266-23-9 3'-[2-amino-4-(4-methoxyphenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl]-5-methoxybiphenyl-3-yl methanesulfonate 
• 1035267-46-9 3'-[2-amino-4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-5-methoxybiphenyl-3-yl methanesulfonate 
• 1035268-74-6 3'-(2-amino-4-(2,6-dimethylpyridin-4-yl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-5-methoxybiphenyl-3-yI methanesulfonate hydrochloride 

Relevant academic research and scientific papers

NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES

This invention relates to novel compounds having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

SUBSTITUTED ISOINDOLES AS BACE INHIBITORS AND THEIR USE

This invention relates to novel compounds having the structural formula I and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

SUBSTITUTED 2-AMINOPYRIMIDINE-4-ONES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A?-RELATED PATHOLOGIES

This invention relates to novel compounds having the structural formula (I) below: [Chemical formula should be inserted here. Please see paper copy] and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds prov

New Compounds 319

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

AMINO-IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Di

AMINO-IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA

This invention relates to novel compounds having the structural formula (I) and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

NEW COMPOUNDS

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.