937634-53-2Relevant academic research and scientific papers
Catalytic Asymmetric Synthesis of Atropisomeric Quinolines through the Friedl?nder Reaction
Hu, Xingena,Jiang, Jun,Lan, Yunjun,Li, Juan,Li, Xinhua,Liu, Hongxin,Wan, Junlin,Xiao, Hong-Ping
, p. 2198 - 2202 (2019)
A phosphoric acid catalyzed atroposelective Friedl?nder reaction was developed in which acetylacetone and a variety of 2′-substituted 2-Aminobenzophenones were successfully employed to give optically active biaryl quinolines in good yields and with high enantioselectivities.
Hf(OTf)4-Catalyzed highly diastereoselective synthesis of 1,3-disubstituted tetralin derivatives via benzylic C(sp3)-H bond functionalization
Yoshida, Taira,Mori, Keiji
supporting information, p. 4319 - 4322 (2017/04/21)
We report a highly diastereoselective synthesis of 1,3-disubstituted tetralin derivatives via Lewis acid catalyzed benzylic C(sp3)-H bond functionalization. The employment of Hf(OTf)4 as an acid catalyst was crucial in the reaction,
Palladium(0)-catalyzed arylative dearomatization of phenols
Rousseaux, Sophie,Garcia-Fortanet, Jorge,Del Aguila Sanchez, Miguel Angel,Buchwald, Stephen L.
, p. 9282 - 9285 (2011/08/04)
The palladium-catalyzed arylative dearomatization of phenols to yield spirocyclohexadienone products in good to excellent yields has been developed. Preliminary results demonstrate that the formation of the spirocyclic all-carbon quaternary center can be accomplished with high levels of enantiocontrol (up to 91% ee).
