937779-90-3

Upstream product

• 1574285-74-7 C₁₈H₁₆BrNO₃ 
• 1248195-40-5 ethyl 3-(3-methylpyridin-2-yl)-3-oxopropanoate 
• 1574285-71-4 C₁₈H₁₇NO₄ 
• 1574285-69-0 C₂₀H₁₉NO₅ 
• 247570-05-4 3-benzyloxy-4-methoxybenzamide 
• 41222-60-0 3-benzyloxy-4-methoxybenzoyl chloride 
• 58452-00-9 3-benzyloxy-4-methoxybenzoic acid 
• 645-08-9 Isovanillic acid 

Relevant academic research and scientific papers

METHOD FOR PRODUCING OXAZOLE COMPOUND

An object of the present invention is to provide a novel method for producing an oxazole compound. The invention relates to a method for producing a compound represented by formula (1): wherein R1 is lower alkyl group or halogen substituted lower alkyl group, R2 is lower alkyl group, R5 is lower alkyl group, R11 is lower alkyl group, halogen substituted lower alkyl group or a group represented by formula: -CY2COOR12, wherein Y is a halogen atom, R12 is an alkali metal atom or lower alkyl group, Ar1 is phenyl group substituted with lower alkyl group, etc., or pyridyl group substituted with lower alkyl group, etc., X2, X3 and X9 are the same or different and are halogen atoms, X4 is a leaving group, and M is an alkali metal atom.

OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION

ABSTRACT The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by -Y1-A1- or -Y2-C(=O)- wherein Y1 is a group such as -C(=O)-, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.