937807-73-3Relevant academic research and scientific papers
Copper-catalyzed synthesis of 2-unsubstituted, N-substituted benzimidazoles
Hirano, Keiichi,Biju, Akkattu T.,Glorius, Frank
supporting information; experimental part, p. 9570 - 9572 (2010/03/24)
(Chemical Equation Presented) An efficient copper-catalyzed intramolecular arylation of formamidines forming 2-unsubstituted benzimidazoles in excellent yields is reported. Sixteen examples bearing sterically demanding substituents on nitrogen like Mes, 2,6-diisopropylphenyl, or 2-tert-butylphenyl and tolerating various functional groups demonstrate the utility of this method.
Highly stereoselective formal [3 + 3] cycloaddition of enals and azomethine imines catalyzed by N-heterocyclic carbenes
Chan, Audrey,Scheidt, Karl A.
, p. 5334 - 5335 (2008/02/04)
N-Heterocyclic carbenes derived from N-mesityl benzimidazolium salts are effective catalysts for generating homoenolate species from α,β-unsaturated aldehydes. The nucleophilic intermediate adds to azomethine imines, and the resulting activated carbonyl u
