938181-77-2

Basic information

• Product Name: C₃₁H₂₇FN₂O₂S
• Synonyms: C₃₁H₂₇FN₂O₂S
• CAS NO: 938181-77-2
• Molecular Weight: 510.632
• Mol File: 938181-77-2.mol

Chemical Properties

• CAS DataBase Reference: C₃₁H₂₇FN₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₂₇FN₂O₂S(938181-77-2)
• EPA Substance Registry System: C₃₁H₂₇FN₂O₂S(938181-77-2)

Safety Data

• Hazardous Substances Data: 938181-77-2(Hazardous Substances Data)

Upstream product

• 938177-13-0 5-bromo-2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-4(3H)-pyrimidinone 
• 162607-20-7 (5-methylthiophen-2-yl)boronic acid 

Downstream Products

• 938180-01-9 2-(3-fluoro-2-hydroxyphenyl)-6-methyl-5-(5-methyl-2-thienyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone 

Relevant articles and documents

Titanium(IV) isopropoxide mediated synthesis of pyrimidin-4-ones

A novel, one-step method for the synthesis of tri- and tetrasubstituted pyrimidin-4-ones is reported. This method involves a titanium(IV)-mediated cyclization involving two sequential condensations of primary and β-ketoamides. The reaction is operationally facile, readily scalable, and offers rapid entry into differentially substituted pyrimidin-4-one scaffolds. The high functional group compatibility allows for substantial diversification in the products generated from this transformation.