93860-61-8 Usage
Description
(3aS,5S,6R,7aR,7bS,9aS,12aS,12bS)-10-[(1S,2R,3S,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one is a complex organic compound belonging to the oxepinone class. It features a cyclic structure with multiple hydroxyl groups and a dihydroxy-1,4,5-trimethylhexyl side chain. (3aS,5S,6R,7aR,7bS,9aS,12aS,12bS)-10-[(1S,2R,3S,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one's specific configuration and stereochemistry contribute to its unique properties and potential biological activity, making it a molecule of interest in pharmaceutical and chemical research.
Uses
Used in Pharmaceutical Research:
(3aS,5S,6R,7aR,7bS,9aS,12aS,12bS)-10-[(1S,2R,3S,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one is used as a potential pharmaceutical candidate due to its unique structure and stereochemistry. Its complex molecular arrangement may offer novel therapeutic applications, particularly in the development of new drugs targeting specific biological pathways.
Used in Chemical Research:
In the field of chemical research, this compound serves as a subject for studying the synthesis, reactivity, and properties of complex organic molecules. Its unique configuration and the presence of multiple hydroxyl groups may provide insights into new chemical reactions and mechanisms, contributing to the advancement of organic chemistry.
Used in Drug Development:
(3aS,5S,6R,7aR,7bS,9aS,12aS,12bS)-10-[(1S,2R,3S,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one is utilized in drug development for its potential as a lead compound. Its complex structure may possess specific binding affinities or interactions with biological targets, which could be harnessed to create new medications for various diseases and conditions.
Used in Material Science:
In material science, this compound may be explored for its potential applications in the development of new materials with unique properties. The presence of hydroxyl groups and the cyclic structure could contribute to the formation of novel materials with specific characteristics, such as improved stability or reactivity, which could be useful in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 93860-61-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,8,6 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 93860-61:
(7*9)+(6*3)+(5*8)+(4*6)+(3*0)+(2*6)+(1*1)=158
158 % 10 = 8
So 93860-61-8 is a valid CAS Registry Number.
93860-61-8Relevant articles and documents
The development and use of a general route to brassinolide, its biosynthetic precursors, metabolites and analogues
Hurski,Ermolovich,Zhabinskii,Khripach
, p. 1446 - 1452 (2015/01/30)
A new method for the construction of steroid side chains through the addition of lithium salts of dithianes to a C-22 aldehyde was developed. An efficient one-pot procedure for the preparation of a suitable C-22 aldehyde from commercial epibrassinolide in three steps in 86% isolated yield was described. Enantioselective hydroxymethylation of isovaleraldehyde and Kulinkovich cyclopropanation of silylated Roche esters were used as key steps for the dithiane syntheses. The method was applied for the preparation of brassinolide, its biosynthetic precursors and metabolites. In addition, a number of brassinosteroids with a double bond in the side chain were prepared as precursors for tritiated derivatives for biosynthetic studies.
The shortest route from ergosterol to 24-epibrassinolide and its 22S,23S-isomer
Traven, V.FS.,Kuznetsova, N.A.,Levinson, E.E.,Podkhalyuzina, N.Ya.
, p. 96 - 98 (2007/10/02)
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Synthesis and biological activity of brassinolide and its 22 beta, 23 beta-isomer: novel plant growth-promoting steroids.
Thompson,Mandava,Meudt,Lusby,Spaulding
, p. 567 - 580 (2007/10/02)
Brassinolide (2 alpha, 3 alpha, 22 alpha, 23 alpha-tetrahydroxy-24 alpha-methyl -B-homo-7-oxa-5 alpha-cholestan-6-one), a novel plant growth-promoting steroid isolated from rape pollen, and its hitherto unknown 22 beta, 23 beta-isomer were synthesized from a C-24 epimeric 60:40 mixture of 22-dehydroxampesterol (24 alpha-methyl) and brassicasterol (24 beta-methyl) from oysters. The method of synthesis favored the formation of the 22 beta, 23 beta-isomer by better than 4:1. Comparative plant growth-promoting capabilities of brassinolide, both natural and synthetic, and its three side chain cis-glycolic isomers in the bean second internode bioassay showed that the natural and synthetic brassinolides were equally active and caused splitting of the internode at the 0.1 microgram level. The least active was the 22 beta, 23 beta-isomer of brassinolide. The isomers with the 22 alpha, 23 alpha and 24 alpha, and the 22 beta, 23 beta and 24 beta configurations were highly active and were required at about 10 times the concentration of brassinolide to cause the same physiological response. In the bean first internode bioassay, an auxin-induced growth test system which employs isolated bean plant segments, the isomer with 22 beta, 23 beta and 24 beta configuration caused a greater response than brassinolide. Two of the four tetrahydroxy ketones obtained in the synthesis of the isomers were also active in both assays.
