939-04-8

Basic information

• Product Name: 5-methyl-3-phenyl-4,5-dihydro-1H-pyrazole
• CAS NO: 939-04-8
• Molecular Weight: 160.219
• Mol File: 939-04-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-3-phenyl-4,5-dihydro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-3-phenyl-4,5-dihydro-1H-pyrazole(939-04-8)
• EPA Substance Registry System: 5-methyl-3-phenyl-4,5-dihydro-1H-pyrazole(939-04-8)

Safety Data

• Hazardous Substances Data: 939-04-8(Hazardous Substances Data)

Upstream product

• 495-41-0 1-phenylbut-2-en-1-one 
• 98-86-2 acetophenone 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 

Downstream Products

• 70395-55-0 1,5-dimethyl-3-phenyl-4,5-dihydro-1H-pyrazole 

Relevant articles and documents

Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T-Type Calcium Channel Blockers

A series of dihydropyrazole derivatives was developed as potent, selective, and brain-penetrating T-type calcium channel blockers. An optimized derivative, compound 6c, was advanced to in vivo studies, where it demonstrated efficacy in the WAG/Rij rat model of generalized nonconvulsive, absence-like epilepsy. Compound 6c was not efficacious in the basolateral amygdala kindling rat model of temporal lobe epilepsy, and it led to prolongation of the PR interval in ECG recordings in rodents.