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1-Bromo-2-(bromomethyl)-4-nitrobenzene is an organic compound with the molecular formula C7H6Br2NO2. It is a brominated derivative of benzene, featuring a nitro group at the para position, a bromine atom at the ortho position, and a bromine atom attached to a methyl group at the meta position. 1-bromo-2-(bromomethyl)-4-nitrobenzene is characterized by its yellowish color and is often used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Due to its reactive nature, it is typically handled with care in a controlled laboratory environment.

939-82-2

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939-82-2 Usage

Appearance

Pale yellow solid

Solubility

Insoluble in water, soluble in organic solvents

Synonyms

4-nitro-1-(bromomethyl)-2-bromobenzene

Uses

a. Synthesis of pharmaceuticals
b. Synthesis of agrochemicals
c. Synthesis of dyes
d. Intermediate in organic chemistry for the production of various compounds

Chemical class

Halogenated aromatic compound

Safety precautions

Requires careful handling due to potential hazards if not used properly

Check Digit Verification of cas no

The CAS Registry Mumber 939-82-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,3 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 939-82:
(5*9)+(4*3)+(3*9)+(2*8)+(1*2)=102
102 % 10 = 2
So 939-82-2 is a valid CAS Registry Number.

939-82-2Relevant articles and documents

(3-(1H-1,2,3-triazole)phenyl)phosphoric acid derivative as well as preparation method and application thereof

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Paragraph 0054, (2021/08/07)

The invention relates to the technical field of medicinal chemistry, and discloses a (3-(1H-1,2,3-triazole)phenyl)phosphoric acid derivative derivative as shown in a formula X which is described in the specification. The derivative has good and broad-spec

Strategy for Overcoming Full Reversibility of Intermolecular Radical Addition to Aldehydes: Tandem C-H and C-O Bonds Cleaving Cyclization of (Phenoxymethyl)arenes with Carbonyls to Benzofurans

Zheng, Hong-Xing,Shan, Xiang-Huan,Qu, Jian-Ping,Kang, Yan-Biao

, p. 3310 - 3313 (2018/06/11)

An intermolecular addition of carbon radicals enabled by a cascade radical coupling strategy is developed. It includes an intermolecular alkyl radical addition to a carbonyl group followed by an intramolecular alkoxy radical addition to haloarenes and produces substituted benzofurans in high yields. The radical nature of this reaction is explored by radical trapping experiments and EPR analysis. The mechanism is investigated by KIE experiments and control experiments. This method could provide rapid and practical access to the key intermediate of TAM-16, a safe and potent antibacterial agent for treating tuberculosis, and, therefore, is of great importance for organic synthesis and the pharmaceutical industry.

CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF

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Paragraph 0513; 0515, (2018/02/01)

The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula (I), or a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof. For Formula (I) compounds R1, R2, R3, Ar and Z are as defined in the specification. The inventive Formula (I) compounds are inhibitors of CK2 and find utility in any number of therapeutic applications, including but not limited to treatment of proliferative disorders such as cancer, inflammation and immunological disorders.

BORON-CONTAINING SMALL MOLECULES

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Page/Page column 152, (2011/06/16)

This invention relates to 6-substituted benzoxaborole compounds of the following formula and their use for treating bacterial infections.

Synthesis of benzo- and naphtho-fused bicyclo[n.3.1]alkane frameworks with a bridgehead nitrogen function by palladium-catalyzed intramolecular α′-arylation of α-nitroketones

Giorgi, Giorgio,Maiti, Swarupananda,Lopez-Alvarado, Pilar,Menendez, J. Carlos

supporting information; experimental part, p. 2722 - 2730 (2011/05/12)

The C-alkylation of cyclic α-nitroketones with α-halobenzyl halides in the presence of DBU followed by a Pd-catalyzed intramolecular C-arylation afforded benzo-and naphtho-fused bicyclo[n.3.1]alkane derivatives (n = 3, 4, 5) in excellent overall yields for the two-step sequence. In some of the reactions starting from α-nitrocyclooctanone, the major products were fused indane derivatives arising from an intramolecular attack of an intermediate Pd species onto the carbonyl group, followed by elimination.

Synthesis, evaluation, and computational studies of naphthalimide-based long-wavelength fluorescent boronic acid reporters

Jin, Shan,Wang, Junfeng,Li, Minyong,Wang, Binghe

experimental part, p. 2795 - 2804 (2009/04/11)

Boronic acids that change fluorescence properties upon sugar binding are very useful for the synthesis of carbohydrate sensors. Along this line, boronic acids that fluoresce beyond 500 nm are especially useful. A series of boronic acid fluorescent reporte

Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: Structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109

Hirashima, Shintaro,Suzuki, Takayoshi,Ishida, Tomio,Noji, Satoru,Yata, Shinji,Ando, Izuru,Komatsu, Masakazu,Ikeda, Satoru,Hashimoto, Hiromasa

, p. 4721 - 4736 (2007/10/03)

Following the discovery of a new series of benzimidazole derivatives bearing a diarylmethyl group as inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase (HCV NS5B RdRp), we extended the structure-activity relationship (SAR) study to analogue

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