93902-63-7

Upstream product

• 92-66-0 4-bromo-1,1'-biphenyl 
• 286-20-4 cyclohexane-1,2-epoxide 
• 3315-91-1 4-biphenylylmagnesium bromide 

Downstream Products

• 93877-01-1 2-((1,1'-biphenyl)-4-yl)cyclohexan-1-one 
• 1165-58-8 o,p-quaterphenyl 
• 5660-43-5 4,4''-diphenyl-o-terphenyl 
• 5660-40-2 Quiniqui<3.2.4>phenyl 
• 95622-40-5 1-Phenyl-2-(4-xenyl)-cyclohexanol 
• 96468-28-9 1,2-Di-(4-Xenyl)-cyclohexanol-⁽¹⁾ 
• 96468-27-8 2-(4-Xenyl)-1-(3-xenyl)-cyclohexanol-⁽¹⁾ 
• 126421-73-6 (+/-)-trans-2-(4-biphenylyl)cyclohexyl 3-oxobutanoate 
• 126421-85-0 (+/-)-trans-2-(4-biphenylyl)cyclohexyl 3-acetamidobutanoate 
• 126421-79-2 (+/-)-trans-2-(4-biphenylyl)cyclohexyl (Z)-3-acetamido-2-butenoate 

Relevant academic research and scientific papers

Method for preparing alcohol through reaction of Suzuki no exogenous alkali (by machine translation)

The method for synthesizing the alcohol compound by. using the method disclosed by the invention for preparing .the alcohol compound by adopting the method Suzuki disclosed by the invention has the advantages that the reaction system, is convenient and convenient, to prepare, and the reaction system is convenient to prepare . Suzuki. (by machine translation)

Diastereoselective and enantioselective alkaline-hydrolysis of 2-aryl-1-cyclohexyl acetate: a CAL-B catalyzed deacylation/acylation tandem process

Candida antarctica lipase proved to be a particularly efficient lipase for the resolution of racemic 2-arylcyclohexyl acetate in hydrolysis reaction with Na2CO3 in an organic medium. The (1R,2S)-trans-2-arylcyclohexanols 2a–2d were obtained with high ee values (up to >99%) and the selectivity reached E > 200. The influence of the enol ester and the solvent on (±)-trans-2-arylcyclohexanol in the CAL-B catalyzed acylation was also studied and compared with the deacylation. The CAL-B exhibits a better affinity for the alkaline hydrolysis reaction compared with acylation with the enol esters in the same organic solvents. The best conditions were applied to resolve a stereoisomeric mixture cis/trans-2-phenyl-1-cyclohexanol and its corresponding acetate by acylation and deacylation. The obtained results show a highly enantio- and diastereoselectivity of the CAL-B during the acylation and the deacylation in favor of the trans-(R)-enantiomer product. The resolution of a mixture of cis/trans-2-arylcyclohexanols was an easy, convenient approach to provide only one stereoisomer of a mixture of four with high enantiomeric excess.

Development of Enantioselective Palladium-Catalyzed Alkene Carboalkoxylation Reactions for the Synthesis of Tetrahydrofurans

The Pd-catalyzed coupling of γ-hydroxyalkenes with aryl bromides affords enantiomerically enriched 2-(arylmethyl)tetrahydrofuran derivatives in good yield and up to 96:4 e.r. This transformation was achieved through the development of a new TADDOL/2-arylcyclohexanol-derived chiral phosphite ligand. The transformations are effective with an array of different aryl bromides, and can be used for the preparation of products bearing quaternary stereocenters.

New chiral auxiliaries: Their use in the asymmetric hydrogenation of β-acetamidocrotonates

Synthesis of chiral β-amido esters 7 with high diasteroisomeric excess was achieved by asymmetric hydrogenation (H2/PtO2) of stereogenic β-acetamidocrotonates 6 in which the chirality is present in the alkyl of the ester part. For such a purpose, new efficient chiral auxiliaries such as 2,2-diphenylcyclopentanol (12) and 1,1-diphenyl-3-methyl-2-butanol (13) were developed.