939983-17-2

Upstream product

• 796875-53-1 4-(tert-butyl)-2-ethoxybenzoic acid 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 1440433-61-3 N-2-amino-1-(4-chlorophenyl)ethyl-4-tert-butyl-2-ethoxybenzamide 
• 1440433-54-4 2-(4-tert-butyl-2-ethoxyphenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-imidazole 

Relevant academic research and scientific papers

Deconstruction of a nutlin: Dissecting the binding determinants of a potent protein-protein interaction inhibitor

Protein-protein interaction (PPI) systems represent a rich potential source of targets for drug discovery, but historically have proven to be difficult, particularly in the lead identification stage. Application of the fragment-based approach may help tow

4,4,5,5, Tetrasubstituted imidazolines

There is provided a compound of formula I and the pharmaceutically acceptable salts and esters thereof wherein X1, X2, R1, R2, R3, R4, R5 and R6 are herein described. The compounds exhibit activity as anticancer agents.