939983-58-1Relevant academic research and scientific papers
IMIDAZOTHIAZOLE DERIVATIVE HAVING PROLINE RING STRUCTURE
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Page/Page column 76; 77, (2011/11/07)
[Problem to be Solved] There is provided a novel compound that inhibits interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity. [Solution] The present invention provides an imidazothiazole derivative rep
IMIDAZOTHIAZOLE DERIVATIVES
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Page/Page column 181-182, (2009/10/01)
There is provided a novel compound that inhibits interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity. The present invention provides an imidazothiazole derivative represented by the following formula
4,4,5,5, Tetrasubstituted imidazolines
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Page/Page column 65/2, (2008/06/13)
There is provided a compound of formula I and the pharmaceutically acceptable salts and esters thereof wherein X1, X2, R1, R2, R3, R4, R5 and R6 are herein described. The compounds exhibit activity as anticancer agents.
