940284-18-4

Usage

Uses

Used in Organic Synthesis:
2-(METHYLTHIO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER is used as a reagent for the preparation of pharmaceutical intermediates and agrochemicals. Its boronic acid functionality allows for selective modification of other molecules in the presence of functional groups such as alcohols and amines, making it a versatile component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(METHYLTHIO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER is used as a key intermediate in the synthesis of various drug molecules. Its ability to form stable complexes with organic compounds enables the development of new pharmaceutical agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 2-(METHYLTHIO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER is utilized as a building block for the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and compatibility with other organic compounds contribute to the development of more effective and targeted agrochemical products.

Upstream product

• 14001-67-3 5-bromo-2-methylthiopyrimidine 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 4874-33-3 2-methylthio-5-hydroxypyrimidine 
• 1246372-77-9 2-(3,4-dimethoxy-phenyl)-5-(2-methylsulfanyl-pyrimidin-5-yl)-imidazo[2,1-b][1,3,4]thiadiazole 
• 1330595-44-2 tert-butyl [trans-4-({3-[2-(methylsulfanyl)pyrimidin-5-yl]imidazo-[1,2-b]pyridazin-6-yl}amino)cyclohexyl]carbamate 
• 1388144-41-9 2-{2-fluoro-4-[2-(methylsulfanyl)pyrimidin-5-yl]phenyl}-6-(trifluoromethyl)-1H-benzimidazole 

Relevant academic research and scientific papers

COMPOUNDS AS DGAT-1 INHIBITORS

Described herein are compounds of formula I. The compounds of formula I act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.

IMIDAZOLE DERIVATIVES

Described herein are compounds of formula I. The compounds of formula I act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.

PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS

Novel compounds of structure Formula (I) or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein Z, R1, R2, R21, T1, T2, T3 and T4 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.

AROMATIC COMPOUND

An aromatic compound represented by the following formula or a pharmaceutically acceptable salt thereof: , wherein ring A is a heterocyclic ring, ring B is a carbocyclic ring, a heterocyclic ring etc., G1, G2, G3, G4 and G5 are CH or N, X is -NH-, -O-, -CH2-, etc., Y is - CH2-,-CO-,-SO2- etc., Z is a single bond, -CO-, -SO2-, -NH-, -O-, -S-, -CONH-,-SO2NH-, etc., R2 is hydrogen, alkyl, alkoxy, halogen, etc., and R3 is carbocyclic group, heterocyclic group, alkyl, etc., is useful as a controlling agent of the function of CCR4 useful for the treatment or therapy for bronchial asthma, atopic dermatitis, etc.