940284-55-9

Usage

Uses

Used in Medicinal Chemistry:
Methyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-3-carboxylate serves as a key building block in the synthesis of new pharmaceutical compounds, contributing to the development of innovative treatments for various diseases and conditions.
Used in Research and Development:
As a research tool, methyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-3-carboxylate aids in the study of pyrazolopyrimidine-based drugs, providing insights into their mechanisms of action, efficacy, and potential side effects.
Used in Chemical Synthesis:
The unique structure of methyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-3-carboxylate makes it an intriguing target for chemical synthesis, where it can be modified or combined with other compounds to create new molecules with specific therapeutic properties.
Used in Drug Development:
In the field of drug development, methyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-3-carboxylate is explored for its potential to be incorporated into new drug candidates, offering novel therapeutic options and advancing the frontiers of medical treatment.

InChI:InChI=1/C8H5Cl2N3O2/c1-15-8(14)4-3-11-13-6(10)2-5(9)12-7(4)13/h2-3H,1H3

Upstream product

• 6994-25-8 3-amino-4-pyrazolecarboxylic acid ethyl ester 
• 90349-67-0 ethyl 5,7-dihydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 1260243-04-6 ethyl 5-amino-1H-pyrazole-4-carboxylate 

Relevant academic research and scientific papers

SUBSTITUTED 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES

The present invention provides a compound of Formula (I) wherein R is (II) or (III), or a pharmaceutically acceptable salt thereof, useful for treating psoriasis, systemic lupus erythematosus, or type 1 diabetes.

7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE COMPOUNDS

The present invention provides a compound of Formula (I) wherein R is (II), (III), (IV) or a pharmaceutically acceptable salt thereof, useful for treating psoriasis, systemic lupus erythematosus, or type 1 diabetes.

PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF PSORIASIS AND SYSTEMIC LUPUS ERYTHEMATOSUS

The present invention provides a compound of Formula I: wherein R is methyl or ethyl; or a pharmaceutically acceptable salt thereof useful for treating psoriasis or systemic lupus erythematosus.

7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES

The present invention provides a compound of Formula (I) wherein R is (II) or (III); or a pharmaceutically acceptable salt thereof, useful for treating psoriasis or systemic lupus erythematosus.

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

TYK2 PSEUDOKINASE LIGANDS

Described herein are TYK2 pseudokinase ligands and methods of utilizing TYK2 pseudokinase ligands in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.

THERAPEUTIC COMPOUNDS

The present disclosure relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R3 have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

AROMATIC COMPOUND

An aromatic compound represented by the following formula or a pharmaceutically acceptable salt thereof: , wherein ring A is a heterocyclic ring, ring B is a carbocyclic ring, a heterocyclic ring etc., G1, G2, G3, G4 and G5 are CH or N, X is -NH-, -O-, -CH2-, etc., Y is - CH2-,-CO-,-SO2- etc., Z is a single bond, -CO-, -SO2-, -NH-, -O-, -S-, -CONH-,-SO2NH-, etc., R2 is hydrogen, alkyl, alkoxy, halogen, etc., and R3 is carbocyclic group, heterocyclic group, alkyl, etc., is useful as a controlling agent of the function of CCR4 useful for the treatment or therapy for bronchial asthma, atopic dermatitis, etc.