940656-93-9Relevant academic research and scientific papers
The synthesis of benzimidazole derivatives in the absence of solvent and catalyst
Yu, Chuanming,Guo, Peng,Jin, Can,Su, Weike
, p. 333 - 336 (2009)
Differently substituted benzimidazoles have been synthesised from o-phenylenediamine and arylaldehydes or arylmethylene-malononitriles absorbed on silica gel. The reaction was carried out by intermittent grinding or by a microwave-assisted technique under solvent- and catalyst-free conditions giving good yields of the products.
A green synthesis of benzimidazoles
Kathirvelan,Yuvaraj,Babu,Nagarajan, Arasampattu S.,Reddy, Boreddy S.R.
, p. 1152 - 1156 (2013/09/24)
Various 2-substituted benzimidazole derivatives in moderate to good yield have been prepared in a one-pot reaction by condensation of o-phenylenediamine and an aldehyde in the presence of ammonium chloride as a catalyst at 80-90°C. The reaction is green and economically viable.
