94067-27-3

Basic information

• Product Name: 7-BENZYLOXYGRAMINE
• Synonyms: 7-BENZYLOXYGRAMINE;7-BENZYLOXY-3-(DIMETHYLAMINOMETHYL)INDOLE;7-BENZYLOXYGRAMINE CRYSTALLINE;N,N-DiMethyl-7-(phenylMethoxy)-1H-indole-3-MethanaMine;NSC 92544
• CAS NO: 94067-27-3
• Molecular Formula: C₁₈H₂₀N₂O
• Molecular Weight: 280.36
• Product Categories: Indoles and derivatives;Amino Acids & Derivatives;Aromatics;Intermediates
• Mol File: 94067-27-3.mol

Chemical Properties

• Boiling Point: 442.3°Cat760mmHg
• Flash Point: 221.3°C
• Appearance: /
• Density: 1.153g/cm³
• Vapor Pressure: 5.06E-08mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 7-BENZYLOXYGRAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BENZYLOXYGRAMINE(94067-27-3)
• EPA Substance Registry System: 7-BENZYLOXYGRAMINE(94067-27-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38-43
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 94067-27-3(Hazardous Substances Data)

Usage

Uses

Intermediate in the preparation of Tryptophan derivatives.

InChI:InChI=1/C18H20N2O/c1-20(2)12-15-11-19-18-16(15)9-6-10-17(18)21-13-14-7-4-3-5-8-14/h3-11,19H,12-13H2,1-2H3

Upstream product

• 20289-27-4 7-benzyloxyindole 
• 50-00-0 formaldehyd 
• 124-40-3 dimethyl amine 

Downstream Products

• 66866-40-8 (+/-)-7-benzyloxytryptophan 
• 858232-85-6 (7-benzyloxy-indol-3-yl)-acetic acid amide 
• 99102-24-6 (7-benzyloxy-indol-3-yl)-acetonitrile 
• 99102-25-7 (7-benzyloxy-indol-3-yl)-acetic acid 
• 173447-79-5 7-Hydroxyindol-3-essigsaeure 
• 31677-75-5 2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine 

Relevant articles and documents

INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE

The compound of the formula (I): wherein W is a group of the following formula (VIII) binding to any possible position on the Q: Q is, together with W, a group of the formula: -C(M=C(R3A)-N(R3)-, etc.; R3A is H or optionally substituted lower alkyl; R4, R5, R6, and R7 are independently H or optionally substituted lower alkyl; R1 is optionally substituted lower alkyl, etc.; R2 is H, etc.; R3 is H, etc.; Ar is phenyl, etc., or a pharmaceutically acceptable salt thereof, where these compounds exhibiting β3-adrenoceptor-stimulating activity and being useful as a medicament for treatment of obesity, etc.