940948-34-5

Upstream product

• 348169-39-1 4-bromo-2-methoxy-6-methyl-phenylamine 
• 1357103-74-2 5-bromo-2-chloro-1-methoxy-3-methylbenzene 
• 940948-33-4 3-bromo-4-chloro-5-methoxyphenylamine 
• 13061-96-6 dihydroxy-methyl-borane 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are

Pyrrolopyridine kinase inhibiting compounds

Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least one of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, Mek1, PDK-1, GSK3β, EGFR, p70S6K, BMX, SGK, CaMKII, Tie-2, IGF-1R, Ron, Met, and KDR kinases in animals, including humans, for the treatment and/or prevention of various diseases and conditions such as cancer.