941269-63-2

Upstream product

• 941269-61-0 C₂₅H₂₀ClNO₅ 
• 100-39-0 benzyl bromide 
• 103797-05-3 N-(3-acetyl-2-hydroxy-5-methyl-phenyl)-acetamide 
• 66422-84-2 4-benzyloxy-3-chlorobenzaldehyde 

Downstream Products

• 372102-45-9 8-amino-3-(benzyloxy)-2-[4-(benzyloxy)-3-chlorophenyl]-6-methyl-4H-chromen-4-one 
• 372102-46-0 2-{3-(benzyloxy)-2-[4-(benzyloxy)-3-chlorophenyl]-6-methyl-4-oxo-4H-chromen-8-yl}-1λ6-isothiazolidin-1,1-dione 

Relevant academic research and scientific papers

3-Hydroxychromones as cyclin-dependent kinase inhibitors: Synthesis and biological evaluation

A novel series of 3-hydroxychromones were prepared and found to be CDK inhibitors. Isothiazolidine 1,1-dioxide analogues showed potent CDK1 and CDK2 inhibitory activities and inhibited proliferation of EJ, HCT116, SW620, and MDAMB468 cancer cells.